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PMM1 Protein (AA 1-262) (His tag)

PMM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667263
  • Target See all PMM1 Proteins
    PMM1 (Phosphomannomutase 1 (PMM1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-262
    Origin
    • 6
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PMM1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    PMM1, 1-262aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product PMM1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 100mM NaCl, 0.1mM PMSF
    Storage
    4 °C
  • Target
    PMM1 (Phosphomannomutase 1 (PMM1))
    Alternative Name
    PMM1 (PMM1 Products)
    Synonyms
    Sec53 Protein, C77612 Protein, phosphomannomutase 1 Protein, phosphomannomutase 1 L homeolog Protein, PMM1 Protein, pmm1 Protein, Pmm1 Protein, pmm1.L Protein
    Background
    PMM1 (Phosphomannomutase 1) is an enzyme that involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. This enzyme catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. In addition, it may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain. Recombinant human PMM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: phosphomannomutase 1, Sec53, PMMH22. NCBI no.: NP_002667
    Molecular Weight
    31.9kDa (282aa) confirmed by MALDI-TOF
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