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NANS Protein (AA 1-359) (His tag)

NANS Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667265
  • Target See all NANS Proteins
    NANS (N-Acetylneuraminic Acid Synthase (NANS))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-359
    Origin
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This NANS protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    NANS, 1-359aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product NANS Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol
    Storage
    4 °C
  • Target
    NANS (N-Acetylneuraminic Acid Synthase (NANS))
    Alternative Name
    NANS (NANS Products)
    Synonyms
    MGC84329 Protein, SAS Protein, N-acetylneuraminate synthase L homeolog Protein, N-acetylneuraminate synthase Protein, nans.L Protein, NANS Protein, Nans Protein
    Background
    NANS, also known as SAS, is a 359 amino acid protein that contains one AFP (antifreeze proteins)-like domain and functions in the biosynthesis of sialic acids. Expressed ubiquitously, NANS enzymatically catalyzes the H2O-dependent formation of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), both of which are sialic acids. NANS uses N-acetylmannosamine 6-phosphate as a substrate for Neu5Ac synthesis and mannose 6-phosphate as a substrate for KDN synthesis. Recombinant human NANS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Sialic acid synthase, SAS, N acetylneuraminate synthase. NCBI no.: NP_061819
    Molecular Weight
    42.4 kDa (379aa) confirmed by MALDI-TOF
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