SMNDC1 Protein (AA 1-238) (His tag)
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- Target See all SMNDC1 Proteins
- SMNDC1 (Survival Motor Neuron Domain Containing 1 (SMNDC1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-238
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SMNDC1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SMNDC1, 1-238aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SMNDC1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT, 100mM NaCl
- Storage
- 4 °C
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- Target
- SMNDC1 (Survival Motor Neuron Domain Containing 1 (SMNDC1))
- Alternative Name
- SMNDC1 (SMNDC1 Products)
- Synonyms
- smnr Protein, spf30 Protein, SMNDC1 Protein, SMNR Protein, SPF30 Protein, TDRD16C Protein, wu:fb37h07 Protein, wu:fc23a07 Protein, 2410004J23Rik Protein, 4933440I19Rik Protein, survival motor neuron domain containing 1 Protein, smndc1 Protein, SMNDC1 Protein, Bm1_41545 Protein, Smndc1 Protein
- Background
- SMNDC1 (survival motor neuron domain containing 1) is an essential splicing factor required for spliceosome assembly that belongs to the SMN family. It contains one Tudor domain with significant similarity to SMN (Survival Motor Neuron) and is expressed in skeletal muscle, pancreas and heart, localizing to Cajal bodies and nuclear speckles. Mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. Recombinant human SMNDC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Survival of motor neuron-related-splicing factor 30, Survival of motor neuron-related-splicing factor 30. NCBI no.: NP_005862
- Molecular Weight
- 28.9kDa (258aa), confirmed by MALDI-TOF
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