BPNT1 Protein (AA 1-308) (His tag)
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- Target See all BPNT1 Proteins
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-308
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BPNT1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- BPNT1, 1-308aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS – PAGE
- Top Product
- Discover our top product BPNT1 Protein
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3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 1-308) protein (His tag)
BPNT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 1-261) protein (GST tag)BPNT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 1-100) protein (GST tag)BPNT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 2-308) protein (His tag)Crystallography grade BPNT1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 2-308) protein (His tag)Crystallography grade BPNT1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) protein (Myc-DYKDDDDK Tag)BPNT1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 5mM DTT, 0.1M NaCl.
- Storage
- 4 °C
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- Target
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
- Alternative Name
- BPNT1 (BPNT1 Products)
- Synonyms
- BPNT1 Protein, PIP Protein, Sal3 Protein, BPntase Protein, 3'(2'), 5'-bisphosphate nucleotidase 1 Protein, bisphosphate 3'-nucleotidase 1 Protein, BPNT1 Protein, bpnt1.L Protein, Bpnt1 Protein
- Background
- BPNT1, also known as BPntase, PAP phosphatase or PIP (PAP-inositol-1,4-phosphatase), is a member of the magnesium-dependent, lithium-sensitive phosphomono-esterase superfamily. Using magnesium as a cofactor, BPNT1 catalyzes the conversion of PAPS (adenosine 3'-phosphate 5' phosphosulfate) to APS (adenosine 5'-phosphosulfate) and the conversion of PAP (3'(2')-phosphoadenosine 5' phosphate) to AMP (adenosine 5'-phosphate). Expressed ubiquitously with highest levels in brain and kidney, BPNT1 is potently inhibited by lithium, a drug used for the treatment of manic depression and bipolar affective disorder, suggesting a possible role for BPNT1 in the etiology of mood disorders. Recombinant human BPNT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: 3'(2'), 5'-bisphosphate nucleotidase 1, PIP, PAP-inositol-1,4-phosphatase. NCBI no.: NP_006076
- Molecular Weight
- 37.5 kDa (344aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- Inositol Metabolic Process
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