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TFAM Protein (AA 43-246) (His tag)

TFAM Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN667339
  • Target See all TFAM Proteins
    TFAM (Transcription Factor A, Mitochondrial (TFAM))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 43-246
    Origin
    • 4
    • 3
    • 3
    • 1
    Human
    Source
    • 8
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This TFAM protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    TFAM, 43-246aa, Human, His tag, E.coli
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product TFAM Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol
    Storage
    4 °C
  • Target
    TFAM (Transcription Factor A, Mitochondrial (TFAM))
    Alternative Name
    TFAM (TFAM Products)
    Synonyms
    tcf6 Protein, mttf1 Protein, mttfa Protein, tcf6l1 Protein, tcf6l2 Protein, tcf6l3 Protein, mttfa-A Protein, xl-mtTFA Protein, MGC153358 Protein, zgc:153358 Protein, MTTF1 Protein, MTTFA Protein, TCF6 Protein, TCF6L1 Protein, TCF6L2 Protein, TCF6L3 Protein, AI661103 Protein, Hmgts Protein, mtTFA Protein, tsHMG Protein, Mttfa Protein, transcription factor A, mitochondrial Protein, transcription factor A, mitochondrial L homeolog Protein, TFAM Protein, tfam.L Protein, tfam Protein, Tfam Protein
    Background
    TFAM, also known as MtTF1 or mtTFA, is a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. TFAM is located primarily in the nuclei of elongated spermatids and may be involved in the regulation of gene expression of the haploid male genome. TFAM has been associated with mitochondrial disorder in humans characterized by ocular myopathy, exercise intolerance and muscle wasting. Recombinant human TFAM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Transcription factor A, mitochondrial precursor, MtTF1, mtTFA, TCF6, TCF6L1, TCF6L2, TCF6L3. NCBI no.: NP_003192
    Molecular Weight
    26.6 kDa (225aa), confirmed by MALDI-TOF
    Pathways
    Chromatin Binding
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