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SUGT1 Protein (AA 115-365) (His tag)

SUGT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667341
  • Target See all SUGT1 Proteins
    SUGT1 (SGT1, Suppressor of G2 Allele of SKP1 (SUGT1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 115-365
    Origin
    • 6
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SUGT1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    SUGT1, 115-365aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product SUGT1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 1mM DTT, 0.1M NaCl
    Storage
    4 °C
  • Target
    SUGT1 (SGT1, Suppressor of G2 Allele of SKP1 (SUGT1))
    Alternative Name
    SUGT1 (SUGT1 Products)
    Synonyms
    SGT1 Protein, 2410174K12Rik Protein, Aa1114 Protein, sugt1 Protein, wu:fd45a02 Protein, zgc:103668 Protein, SGT1 homolog, MIS12 kinetochore complex assembly cochaperone Protein, SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) Protein, SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) pseudogene Protein, suppressor of G2 allele of SKP1 homolog Protein, protein SGT1 homolog Protein, SGT1 disease resistance protein homolog1 Protein, SUGT1 Protein, Sugt1 Protein, LOC100402050 Protein, LOC100512856 Protein, LOC100631434 Protein, LOC100645570 Protein, IDP1602 Protein, sgut1 Protein
    Background
    SUGT1, also known as suppressor of G2 allele of SKP1, is a homolog of the yeast protein SGT1, a regulator of the cell cycle that is essential for G1/S and G2/M transitions. It contains a CS domain, a SGS domain, a p23 domain and three tetratricopeptide repeats (TPR). This protein associates with Skp1 p19 and CUL-1, subunits of the SCF ubiquitin ligase complex, and is thought to play a role in protein degradation. In addition, it is required for the kinetochores assembly, and has function as a co-chaperone for HSP90. Recombinant human SUGT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Suppressor of G2 allele of SKP1 homolog isoform SGT1B, SGT1. NCBI no.: NP_001124384
    Molecular Weight
    30.7 kDa (272aa), confirmed by MALDI-TOF
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