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ALKBH3 Protein (AA 1-286) (His tag)

ALKBH3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667398
  • Target See all ALKBH3 Proteins
    ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-286
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This ALKBH3 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    ALKBH3, 1-286aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product ALKBH3 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
    Storage
    4 °C
  • Target
    ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
    Alternative Name
    ALKBH3 (ALKBH3 Products)
    Synonyms
    ABH3 Protein, DEPC-1 Protein, DEPC1 Protein, PCA1 Protein, 1700108H04Rik Protein, 1810020C19Rik Protein, Abh3 Protein, mABH3 Protein, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase L homeolog Protein, alkB homolog 3, alpha-ketoglutaratedependent dioxygenase Protein, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase Protein, alkbh3.L Protein, ALKBH3 Protein, Alkbh3 Protein
    Background
    ALKBH3 is a member of the ALKB family of proteins and functions as a dioxygenase with a preference for RNA and single stranded DNA substrates. This protein repairs 1-methyladenine and 3-methylcytosine lesions in alkylated DNA and RNA and its activity is stimulated by ascorbate. ALKBH3 is expressed in a wide variety of tissues and localizes to the cytoplasm and the nucleus. Recombinant human ALKBH3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, ABH3, DEPC-1, DEPC1, PCA1. NCBI no.: NP_631917
    Molecular Weight
    37.9 kDa (325aa), confirmed by MALDI-TOF
    Pathways
    DNA Damage Repair
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