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PTGDS Protein (AA 23-190) (His tag)

PTGDS Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667417
  • Target See all PTGDS Proteins
    PTGDS (Prostaglandin D2 Synthase (PTGDS))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 23-190
    Origin
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 9
    • 7
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PTGDS protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    PTGDS, 23-190aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product PTGDS Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by BCA assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 1mM EDTA, 0.1M NaCl
    Storage
    4 °C
  • Target
    PTGDS (Prostaglandin D2 Synthase (PTGDS))
    Alternative Name
    PTGDS (PTGDS Products)
    Synonyms
    6PGD Protein, GSTS Protein, GSTS1-1 Protein, PGD2 Protein, PGDS Protein, L-PGDS Protein, LPGDS Protein, PDS Protein, PGDS2 Protein, H-PGDS Protein, Ptgds2 Protein, 21kDa Protein, Ptgs3 Protein, PH2DISO Protein, phosphogluconate dehydrogenase Protein, hematopoietic prostaglandin D synthase Protein, prostaglandin D2 synthase Protein, prostaglandin D2 synthase (brain) Protein, prostaglandin D synthase Protein, prostaglandin D2 synthase 21kDa (brain) Protein, PGD Protein, HPGDS Protein, PTGDS Protein, Hpgds Protein, Ptgds Protein, LOC100009453 Protein
    Background
    Prostaglandin-H2 D-isomerase, also known as PTGDS, is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a beta-amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimer’s disease. Recombinant human PTGDS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Prostaglandin-H2 D-isomerase, L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2. NCBI no.: NP_000945
    Molecular Weight
    20.9 kDa (189aa), confirmed by MALDI-TOF
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