EIF2B1 Protein (AA 1-305) (His tag)
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- Target See all EIF2B1 Proteins
- EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-305
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This EIF2B1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- EIF2B1, 1-305aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product EIF2B1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl
- Storage
- 4 °C
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- Target
- EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))
- Alternative Name
- EIF2B1 (EIF2B1 Products)
- Synonyms
- DDBDRAFT_0219393 Protein, DDBDRAFT_0231375 Protein, DDB_0219393 Protein, DDB_0231375 Protein, 26kDa Protein, D5Ertd406e Protein, EIF2B Protein, EIF2BA Protein, eIF-2a Protein, translation initiation factor eIF-2B alpha subunit Protein, hypothetical protein Protein, Translation initiation factor eIF-2B subunit alpha Protein, eukaryotic translation initiation factor 2B subunit alpha Protein, eukaryotic translation initiation factor 2B, subunit 1 (alpha) Protein, eIF2b1 Protein, PGTG_05021 Protein, ei2ba Protein, eif2b1 Protein, Eif2b1 Protein, EIF2B1 Protein
- Background
- EIF2B1 is one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Phosphorylation of eIF2 inhibits GEF activity of EIF2B, an inhibition that requires the eIF2B1 subunit. Defects in eIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM), a brain disease that is characterized by head trauma and motor deterioration. Recombinant human EIF2B1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kD, EIF-2B, EIF-2Balpha, EIF2B, EIF2BA, MGC117409, MGC125868, MGC125869. NCBI no.: NP_001405
- Molecular Weight
- 35.8 kDa(325aa) confirmed by MALDI-TOF
- Pathways
- Methionine Biosynthetic Process
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