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ATF3 Protein (AA 1-181)

ATF3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667497
  • Target See all ATF3 Proteins
    ATF3 (Activating Transcription Factor 3 (ATF3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-181
    Origin
    • 6
    • 3
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Characteristics
    ATF3, 1-181aa, Human, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product ATF3 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl, pH8.0, 2M Urea, 20%Glycerol
    Storage
    4 °C
  • Target
    ATF3 (Activating Transcription Factor 3 (ATF3))
    Alternative Name
    ATF3 (ATF3 Products)
    Synonyms
    zgc:55526 Protein, ATF3 Protein, LRG-21 Protein, LRF-1 Protein, LRFI Protein, atf-3 Protein, activating transcription factor 3 Protein, activating transcription factor 3 L homeolog Protein, atf3 Protein, ATF3 Protein, Atf3 Protein, atf3.L Protein
    Background
    ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter. Synonyms: Activating transcription factor 3, ATF3deltaZip2, ATF3deltaZip2c, ATF3deltaZip3, cAMP dependent transcription factor ATF3, Cyclic AMP dependent transcription factor ATF3, Cyclic AMP-dependent transcription factor ATF-3. NCBI no.: NP_001665
    Molecular Weight
    20.6kDa (181aa)
    Pathways
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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