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LAT Protein (AA 28-233) (His tag)

LAT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN7279583
  • Target See all LAT Proteins
    LAT (Linker For Activation of T Cells (LAT))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 28-233
    Origin
    • 5
    • 4
    • 2
    Human
    Source
    • 5
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This LAT protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    LAT, 28-233 aa , Human,His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product LAT Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 1mM DTT
    Storage
    4 °C
  • Target
    LAT (Linker For Activation of T Cells (LAT))
    Alternative Name
    LAT (LAT Products)
    Synonyms
    LAT Protein, lat Protein, LAT1 Protein, pp36 Protein, linker for activation of T-cells Protein, linker for activation of T cells Protein, LAT Protein, lat Protein, Lat Protein
    Background
    LAT is an integral membrane protein which is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells. Recombinant human LAT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: linker for activation of T-cells family member 1 isoform b, LAT1, pp36. NCBI no.: NP_001014987
    Molecular Weight
    24.4 kDa (227aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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