LAT Protein (AA 28-233) (His tag)
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- Target See all LAT Proteins
- LAT (Linker For Activation of T Cells (LAT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-233
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LAT protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- LAT, 28-233 aa , Human,His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product LAT Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 1mM DTT
- Storage
- 4 °C
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- Target
- LAT (Linker For Activation of T Cells (LAT))
- Alternative Name
- LAT (LAT Products)
- Synonyms
- LAT Protein, lat Protein, LAT1 Protein, pp36 Protein, linker for activation of T-cells Protein, linker for activation of T cells Protein, LAT Protein, lat Protein, Lat Protein
- Background
- LAT is an integral membrane protein which is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells. Recombinant human LAT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: linker for activation of T-cells family member 1 isoform b, LAT1, pp36. NCBI no.: NP_001014987
- Molecular Weight
- 24.4 kDa (227aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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