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SRGN Protein (AA 28-158) (His tag)

SRGN Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667582
  • Target See all SRGN Proteins
    SRGN (serglycin (SRGN))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 28-158
    Origin
    • 5
    • 3
    • 1
    Human
    Source
    • 5
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SRGN protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    SRGN, 28-158 aa , Human, His tag E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product SRGN Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.15M NaCl.
    Storage
    4 °C
  • Target
    SRGN (serglycin (SRGN))
    Alternative Name
    SRGN (SRGN Products)
    Synonyms
    PPG Protein, PRG Protein, PRG1 Protein, Prg Protein, Prg1 Protein, Sgc Protein, Pgsg Protein, serglycin Protein, SRGN Protein, Srgn Protein
    Background
    SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. Recombinant human SRGN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Serglycin precursor, FLJ12930, MGC9289, PPG, PRG, PRG1. NCBI no.: NP_002718
    Molecular Weight
    17.4 kDa (156aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
    Pathways
    Maintenance of Protein Location
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