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Adenylosuccinate Lyase Protein (ADSL) (AA 1-484) (His tag)

ADSL Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667599
  • Target See all Adenylosuccinate Lyase (ADSL) Proteins
    Adenylosuccinate Lyase (ADSL)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-484
    Origin
    • 6
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Adenylosuccinate Lyase protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    ADSL, 1-484aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product ADSL Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 0.1M NaCl
    Storage
    4 °C
  • Target
    Adenylosuccinate Lyase (ADSL)
    Alternative Name
    ADSL (ADSL Products)
    Synonyms
    fi60b04 Protein, zgc:56061 Protein, wu:fi60b04 Protein, MGC53383 Protein, MGC69239 Protein, adsL Protein, F15C21.8 Protein, F15C21_8 Protein, AMPS Protein, ASASE Protein, ASL Protein, Adl Protein, Asl Protein, purB Protein, adenylosuccinate lyase Protein, adenylosuccinate lyase L homeolog Protein, adenylosuccinase; ASL Protein, Adenylosuccinate lyase Protein, L-Aspartase-like family protein Protein, ADSL Protein, adsl Protein, adsl.L Protein, ASL Protein, purB Protein, purB,adsL Protein, Mrub_2293 Protein, MMAH_RS02975 Protein, Arnit_0089 Protein, Mesil_1058 Protein, Slip_0597 Protein, Trad_2452 Protein, Deba_0652 Protein, Toce_1174 Protein, Acear_2324 Protein, Igag_0272 Protein, Saut_2156 Protein, Fbal_1996 Protein, Ndas_2434 Protein, Ilyop_0196 Protein, Lbys_2961 Protein, MFER_RS02920 Protein, Palpr_2192 Protein, Calni_0061 Protein, Ftrac_3746 Protein, AT1G36280 Protein, Olsu_1764 Protein, Adsl Protein
    Background
    Adenylosuccinate lyase, also known as ADSL, is an enzyme that converts adenylosuccinate to AMP and fumarate as part of the purine nucleotide cycle. Defects in ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency). ADSL deficiency is an autosomal recessive disorder characterized by the accumulation in the body fluids of succinylaminoimidazole-carboxamide riboside (SAICA-riboside) and succinyladenosine (S-Ado). Recombinant human ADSL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Adenylosuccinate lyase, AMPS, ASASE, ASL. NCBI no.: NP_000017
    Molecular Weight
    59 kDa (520aa)
    Pathways
    Ribonucleoside Biosynthetic Process
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