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GMDS Protein (AA 1-372) (His tag)

GMDS Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667602
  • Target See all GMDS Proteins
    GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-372
    Origin
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GMDS protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    GMDS, 1-372aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product GMDS Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.1M NaCl,1mM DTT, 0.1mM PMSF
    Storage
    4 °C
  • Target
    GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))
    Alternative Name
    GMDS (GMDS Products)
    Synonyms
    BC031788 Protein, C87208 Protein, GMD Protein, SDR3E1 Protein, GDP-mannose 4, 6-dehydratase Protein, GDP-mannose 4,6-dehydratase Protein, Gmds Protein, GMDS Protein
    Background
    GMDS, also known as SDR3E1, belongs to the GDP-mannose 4,6-dehydratase family. This protein utilizes NADP as a cofactor to catalyze the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose. Mutations in the gene encoding GMDS are involved in resistance to TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis. Recombinant human GMDS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: GDP-mannose 4,6 dehydratase, GMD, SDR3E1. NCBI no.: NP_001491
    Molecular Weight
    44.1 kDa (392aa), confirmed by MALDI-TOF
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