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SHMT1 Protein (AA 1-483) (His tag)

SHMT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667617
  • Target See all SHMT1 Proteins
    SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-483
    Origin
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SHMT1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    SHMT1, 1-483aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product SHMT1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
    Storage
    4 °C
  • Target
    SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))
    Alternative Name
    SHMT1 (SHMT1 Products)
    Synonyms
    Shmt Protein, mShmt Protein, LRRGT00032 Protein, shmt1 Protein, MGC53442 Protein, zgc:66171 Protein, zgc:77524 Protein, SHMT1 Protein, Shmt1 Protein, CSHMT Protein, SHMT Protein, AI324848 Protein, AI385541 Protein, C81125 Protein, mshmt Protein, mshmt1 Protein, mshmt2 Protein, MEL-32 Protein, SHMT2 Protein, F20D10.50 Protein, F20D10_50 Protein, SERINE HYDROXYMETHYLTRANSFERASE 1 Protein, SERINE TRANSHYDROXYMETHYLASE Protein, SERINE TRANSHYDROXYMETHYLTRANSFERASE Protein, STM Protein, serine transhydroxymethyltransferase 1 Protein, serine hydroxymethyltransferase 1 Protein, serine hydroxymethyltransferase 1 (soluble) L homeolog Protein, serine hydroxymethyltransferase 1 (soluble) Protein, microRNA 6778 Protein, serine transhydroxymethyltransferase 1 Protein, Shmt1 Protein, shmt1.L Protein, shmt1 Protein, MIR6778 Protein, SHMT1 Protein, SHM1 Protein
    Background
    Serine hydroxymethyltransferase 1, also known as SHMT1, belongs to the SHMT family. This protein is cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5 10-methylene tetrahydrofolate. Also, SHMT1 preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate and inhibits. Recombinant human SHMT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Serine hydroxymethyltransferase 1, CSHMT, SHMT. NCBI no.: AAH07979
    Molecular Weight
    55.2 kDa (503aa)
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