SHMT1 Protein (AA 1-483) (His tag)
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- Target See all SHMT1 Proteins
- SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-483
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SHMT1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SHMT1, 1-483aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product SHMT1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
- Storage
- 4 °C
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- Target
- SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))
- Alternative Name
- SHMT1 (SHMT1 Products)
- Synonyms
- Shmt Protein, mShmt Protein, LRRGT00032 Protein, shmt1 Protein, MGC53442 Protein, zgc:66171 Protein, zgc:77524 Protein, SHMT1 Protein, Shmt1 Protein, CSHMT Protein, SHMT Protein, AI324848 Protein, AI385541 Protein, C81125 Protein, mshmt Protein, mshmt1 Protein, mshmt2 Protein, MEL-32 Protein, SHMT2 Protein, F20D10.50 Protein, F20D10_50 Protein, SERINE HYDROXYMETHYLTRANSFERASE 1 Protein, SERINE TRANSHYDROXYMETHYLASE Protein, SERINE TRANSHYDROXYMETHYLTRANSFERASE Protein, STM Protein, serine transhydroxymethyltransferase 1 Protein, serine hydroxymethyltransferase 1 Protein, serine hydroxymethyltransferase 1 (soluble) L homeolog Protein, serine hydroxymethyltransferase 1 (soluble) Protein, microRNA 6778 Protein, serine transhydroxymethyltransferase 1 Protein, Shmt1 Protein, shmt1.L Protein, shmt1 Protein, MIR6778 Protein, SHMT1 Protein, SHM1 Protein
- Background
- Serine hydroxymethyltransferase 1, also known as SHMT1, belongs to the SHMT family. This protein is cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5 10-methylene tetrahydrofolate. Also, SHMT1 preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate and inhibits. Recombinant human SHMT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Serine hydroxymethyltransferase 1, CSHMT, SHMT. NCBI no.: AAH07979
- Molecular Weight
- 55.2 kDa (503aa)
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