HMGCL Protein (AA 28-325) (His tag)
-
- Target See all HMGCL Proteins
- HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-325
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HMGCL protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- HMGCL, 28-325aa , Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product HMGCL Protein
-
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL) (AA 1-325) protein (GST tag)
HMGCL Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL) (AA 28-325) protein (His tag)Crystallography grade HMGCL Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL) (AA 28-325) protein (His tag)Crystallography grade HMGCL Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL) protein (Myc-DYKDDDDK Tag)HMGCL Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.4M Urea
- Storage
- 4 °C
-
- Target
- HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))
- Alternative Name
- HMGCL (HMGCL Products)
- Synonyms
- Afu7g01720 Protein, AO090038000541 Protein, AW476067 Protein, HL Protein, zgc:56248 Protein, 3-hydroxymethyl-3-methylglutaryl-CoA lyase S homeolog Protein, 3-hydroxymethyl-3-methylglutaryl-CoA lyase Protein, 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase Protein, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase Protein, hmgcl.S Protein, HMGCL Protein, AFUA_7G01720 Protein, NFIA_114450 Protein, ACLA_065820 Protein, AOR_1_910074 Protein, PMAA_004600 Protein, TSTA_103060 Protein, ARB_04874 Protein, TRV_06573 Protein, Hmgcl Protein, hmgcl Protein
- Background
- HMGCL, also known as hydroxymethylglutaryl-CoA lyase, is a mitochondrial matrix protein that belongs to the HMG-CoA lyase family. It exists as a homodimer and participates in leucine catabolism and ketogenesis, the hepatic synthesis of ketone bodies that, during fasting, provide a major source of energy for heart, brain and kidney. More specifically, it catalyzes the final step of these processes, the cleavage of 3-hydroxy-3-methylglutaryl-CoA to acetoacetic acid and acetyl-CoA. Recombinant human HMGCL protein, fused to His-tag at N-terminus, was expressed in E.coli. Synonyms: Hydroxymethylglutaryl-CoA lyase, 3-hydroxy-3-methylglutarate-CoA lyase, HL, HMG-CoA lyase, Hydroxymethylglutaryl-CoA lyase mitochondrial. NCBI no.: NP_000182
- Molecular Weight
- 34.2 kDa (323aa)
-
