CYB5R3 Protein (AA 27-301) (His tag)

Catalog No. ABIN667656

Product Details

Target: CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

Protein Type: Recombinant

Protein Characteristics: AA 27-301

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CYB5R3 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: CYB5R3, 27-301 aa, Human, His tag, E.coli

Purity: > 95 % by SDS – PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford)

Buffer: : Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.

Storage: 4 °C

Target Details

Target: CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

Alternative Name: CYB5R3 (CYB5R3 Products)

Synonyms: B5R Protein, DIA1 Protein, Dia1 Protein, Nadhcb5 Protein, RNNADHCB5 Protein, 0610016L08Rik Protein, 2500002N19Rik Protein, C85115 Protein, Dia-1 Protein, WU:AL591952.1-001 Protein, WU:AL591952.1-002 Protein, WU:AL591952.1-003 Protein, WU:Cyb5r3 Protein, fc32h03 Protein, zgc:77071 Protein, wu:fc32h03 Protein, dia1 Protein, CB5R Protein, DDBDRAFT_0218707 Protein, DDBDRAFT_0266821 Protein, DDB_0218707 Protein, DDB_0266821 Protein, cytochrome b5 reductase 3 Protein, cytochrome b5 reductase 3 L homeolog Protein, NADH-cytochrome b5 reductase Protein, CYB5R3 Protein, Cyb5r3 Protein, cyb5r3 Protein, cyb5r3.L Protein, CNM00240 Protein, Tb11.47.0018 Protein, cyb5r1 Protein

Background: CYB5R3 is a cytochrome b5 reductasecytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Mutations in this gene cause methemoglobinemias. Recombinant human CYB5R3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Cytochrome b5 reductase 3., B5R, DIA1. NCBI no.: NP_000389

Molecular Weight: 34 kDa (300 aa) confirmed by MALDI-TOF

Pathways: SARS-CoV-2 Protein Interactome