NKIRAS1 Protein (AA 1-192) (His tag)
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- Target See all NKIRAS1 Proteins
- NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-192
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NKIRAS1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- NKIRAS1, 1-192aa , Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product NKIRAS1 Protein
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NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) (AA 1-192) protein (His tag)
NKIRAS1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) (AA 1-100) protein (GST tag)NKIRAS1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) (AA 1-192) protein (Strep Tag)Crystallography grade NKIRAS1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) protein (Myc-DYKDDDDK Tag)NKIRAS1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
- Storage
- 4 °C
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- Target
- NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
- Alternative Name
- NKIRAS1 (NKIRAS1 Products)
- Synonyms
- NKIRAS1 Protein, KBRAS1 Protein, kappaB-Ras1 Protein, zgc:92823 Protein, kbras1 Protein, 2400004O09Rik Protein, NFKB inhibitor interacting Ras like 1 Protein, NFKB inhibitor interacting Ras-like 1 Protein, NFKB inhibitor interacting Ras-like 1 S homeolog Protein, NFKB inhibitor interacting Ras-like protein 1 Protein, NKIRAS1 Protein, nkiras1 Protein, nkiras1.S Protein, Nkiras1 Protein
- Background
- NKIRAS1, also known as NF-kappa-B inhibitor-interacting Ras-like protein 1, belongs to the small GTPase superfamily. NKIRAS1 is atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. It may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Recombinant human NKIRAS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: NF-kappa-B inhibitor-interacting Ras-like protein 1, kappaB-Ras1, KBRAS1. NCBI no.: NP_065078
- Molecular Weight
- 23.8 kDa (212aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
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