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NFKBIB Protein (AA 1-356) (His tag)

NFKBIB Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667688
  • Target See all NFKBIB Proteins
    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-356
    Origin
    • 7
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This NFKBIB protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    NFKBIB, 1-356aa , Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product NFKBIB Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
    Storage
    4 °C
  • Target
    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
    Alternative Name
    NFKBIB (NFKBIB Products)
    Synonyms
    NFKBIB Protein, IKB-beta Protein, IKappaBbeta Protein, IkB Protein, IkBb Protein, IKBB Protein, TRIP9 Protein, NFKB inhibitor beta Protein, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta Protein, NFKBIB Protein, Nfkbib Protein
    Background
    NFKBIB, also known as NF-kappa-B inhibitor beta, belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Recombinant human NFKBIB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: IKBB, TRIP9. NCBI no.: NP_002494
    Molecular Weight
    40.3 kDa (380aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
    Pathways
    NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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