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CPI-17 Protein (AA 1-147) (His tag)

PPP1R14A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667711
  • Target See all CPI-17 (PPP1R14A) Proteins
    CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-147
    Origin
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CPI-17 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    PPP1R14A , 1-147aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product PPP1R14A Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid in 20mM Tris pH 8.0, 2mM EDTA, 1mM DTT, 10% glycerol
    Storage
    4 °C
  • Target
    CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))
    Alternative Name
    PPP1R14A (PPP1R14A Products)
    Synonyms
    MGC81874 Protein, cpi-17 Protein, ppp1inl Protein, CPI-17 Protein, im:7147597 Protein, ppp1r14a Protein, zgc:110700 Protein, PPP1R14A Protein, CPI17 Protein, PPP1INL Protein, Cpi17 Protein, 1110001M11Rik Protein, protein phosphatase 1 regulatory inhibitor subunit 14A L homeolog Protein, protein phosphatase 1 regulatory inhibitor subunit 14A Protein, protein phosphatase 1, regulatory (inhibitor) subunit 14Aa Protein, protein phosphatase 1, regulatory (inhibitor) subunit 14A Protein, ppp1r14a.L Protein, ppp1r14a Protein, ppp1r14aa Protein, PPP1R14A Protein, Ppp1r14a Protein
    Background
    PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization. Recombinant His tagged PPP1R14A was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CPI17, CPI-17, PPP1INL, Protein phosphatase 1, regulatory (inhibitor) subunit 14A, PPP1R14A , Protein phosphatase 1, regulatory (inhibitor) subunit 14A CPI 17, CPI 17 alpha, CPI 17alpha, CPI17, PKC potentiated inhibitory protein of PP1, Protein phosphatase 1 regulatory (inhibitor) subunit 14A, Protein phosphatase 1 regulatory subunit 14A, Regulatory subunit 14A,. NCBI no.: NP_150281
    Molecular Weight
    18 kDa (167 aa), confirmed by MALDI-TOF.
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