DDIT3 Protein (AA 1-169) (His tag)
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- Target See all DDIT3 Proteins
- DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-169
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DDIT3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- GADD153,1-169aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product DDIT3 Protein
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DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-169) protein (GST tag)
DDIT3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-90) protein (GST tag)DDIT3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 94-155) protein (GST tag)DDIT3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-168) protein (Strep Tag)Crystallography grade DDIT3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid in 20mM Tris pH8.0, 20% Glycerol
- Storage
- 4 °C
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- Target
- DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
- Alternative Name
- GADD153 (DDIT3 Products)
- Synonyms
- chop Protein, Xchop Protein, cebpz Protein, chop10 Protein, gadd153 Protein, CHOP-10 Protein, CHOP10 Protein, CHOP Protein, Chop10 Protein, Gadd153 Protein, CEBPZ Protein, GADD153 Protein, DNA damage inducible transcript 3 Protein, DNA-damage inducible transcript 3 Protein, DNA damage inducible transcript 3 L homeolog Protein, ddit3 Protein, Ddit3 Protein, DDIT3 Protein, ddit3.L Protein
- Background
- GADD153, also known as DNA-damage-inducible transcript 3 (DDIT3), is a basic domain-leucine zipper(bZIP) transcription factor of C/EBP family. This protein has been shown to be up-regulated by several stresses, such as amino acid or glucose starvation, endoplasmic reticulum (ER) stress, osmotic stress and hypoxia. GADD153 protein may play a role in ER stress-mediated apoptosis and in disease including diabetes, brain ischemia and neurodegenerative disease. Recombinant GADD153 fused with His-tag, was expressed in E.coli and purified by conventional chromatography techniques. Synonyms: CHOP, DDIT3, CEBPZ, CHOP10, MGC4154, Growth arrest-and DNA damage-inducible gene 153, GADD153, Growth arrest-and DNA damage-inducible gene 153 C/EBP homologous protein, C/EBP Homology Protein, CHOP 10, DDIT 3, DNA Damage Inducible Transcript 3, GADD 153, Growth Arrest and DNA Damage Inducible Protein 153,. NCBI no.: NP_004074
- Molecular Weight
- 21.3kDa (189aa), confirmed by MALDI-TOF.
- Pathways
- Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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