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SMAD2 Protein (AA 1-467) (His tag)

SMAD2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667736
  • Target See all SMAD2 Proteins
    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-467
    Origin
    • 10
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SMAD2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    SMAD2, 1- 467 aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product SMAD2 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 100 mM NaCl
    Storage
    4 °C
  • Target
    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
    Alternative Name
    SMAD2 (SMAD2 Products)
    Synonyms
    JV18 Protein, JV18-1 Protein, MADH2 Protein, MADR2 Protein, hMAD-2 Protein, hSMAD2 Protein, jv18 Protein, Xmad2 Protein, madh2 Protein, madr2 Protein, XSmad2 Protein, hmad-2 Protein, hsmad2 Protein, jv18-1 Protein, smad-2 Protein, fj43c06 Protein, wu:fj43c06 Protein, 7120426M23Rik Protein, Madh2 Protein, Madr2 Protein, Smad-2 Protein, mMad2 Protein, MAD homolog 2 Protein, Mothers against DPP homolog 2 Protein, SMAD 2 Protein, Smad2 Protein, SMAD family member 2 Protein, SMAD family member 2-Z Protein, SMAD family member 2 S homeolog Protein, SMAD2 Protein, SMAD2Z Protein, smad2 Protein, smad2.S Protein, Smad2 Protein
    Background
    SMAD2(Mothers against decapentaplegic homolog 2) belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. Phosphorylated Smad2 is then able to form a complex with Smad4 or SARA. These complexes accumulate in the cell nucleus, where they are directly participating in the regulation of gene expression. Recombinant SMAD2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Sma- and Mad-related protein 2 isoform 1, hMAD-2, hSMAD2, JV18, JV18-1, MADH2, MADR2, Sma- and Mad-related protein 2 isoform 1 JV181, MAD, MAD Related Protein 2, SMAD2. NCBI no.: NP_005892
    Molecular Weight
    54.4 kDa (487aa)
    Pathways
    Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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