SMAD2 Protein (AA 1-467) (His tag)
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- Target See all SMAD2 Proteins
- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-467
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SMAD2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SMAD2, 1- 467 aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product SMAD2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 100 mM NaCl
- Storage
- 4 °C
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- Target
- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
- Alternative Name
- SMAD2 (SMAD2 Products)
- Synonyms
- JV18 Protein, JV18-1 Protein, MADH2 Protein, MADR2 Protein, hMAD-2 Protein, hSMAD2 Protein, jv18 Protein, Xmad2 Protein, madh2 Protein, madr2 Protein, XSmad2 Protein, hmad-2 Protein, hsmad2 Protein, jv18-1 Protein, smad-2 Protein, fj43c06 Protein, wu:fj43c06 Protein, 7120426M23Rik Protein, Madh2 Protein, Madr2 Protein, Smad-2 Protein, mMad2 Protein, MAD homolog 2 Protein, Mothers against DPP homolog 2 Protein, SMAD 2 Protein, Smad2 Protein, SMAD family member 2 Protein, SMAD family member 2-Z Protein, SMAD family member 2 S homeolog Protein, SMAD2 Protein, SMAD2Z Protein, smad2 Protein, smad2.S Protein, Smad2 Protein
- Background
- SMAD2(Mothers against decapentaplegic homolog 2) belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. Phosphorylated Smad2 is then able to form a complex with Smad4 or SARA. These complexes accumulate in the cell nucleus, where they are directly participating in the regulation of gene expression. Recombinant SMAD2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Sma- and Mad-related protein 2 isoform 1, hMAD-2, hSMAD2, JV18, JV18-1, MADH2, MADR2, Sma- and Mad-related protein 2 isoform 1 JV181, MAD, MAD Related Protein 2, SMAD2. NCBI no.: NP_005892
- Molecular Weight
- 54.4 kDa (487aa)
- Pathways
- Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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