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Frataxin Protein (FXN) (AA 42-210) (His tag)

FXN Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE SDS
Catalog No. ABIN667758
  • Target See all Frataxin (FXN) Proteins
    Frataxin (FXN)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 42-210
    Origin
    • 10
    • 4
    • 2
    • 1
    Human
    Source
    • 10
    • 3
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Frataxin protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    Frataxin, 42-210aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product FXN Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.
    Storage
    4 °C
  • Target
    Frataxin (FXN)
    Alternative Name
    Frataxin (FXN Products)
    Synonyms
    zgc:158218 Protein, LOC100284365 Protein, BcDNA:AT09528 Protein, CG8971 Protein, DFH Protein, Dfh Protein, Dmel\\CG8971 Protein, X25 Protein, dfh Protein, CyaY Protein, FA Protein, FARR Protein, FRDA Protein, RGD1565754 Protein, Frda Protein, frataxin Protein, fxn Protein, LOC100284365 Protein, TVAG_182150 Protein, fh Protein, FTX1 Protein, FXN Protein, Fxn Protein
    Background
    Frataxin, also known as FXN, is an iron binding protein which belongs to FRATAXIN family. It is an anti-apoptotic protein which prevents mitochondrial damage, reactive oxygen species production and act as either an iron chaperone or an iron storage protein. Frataxin is localized to the mitochondrion and regulating mitochondrial iron transport and respiration. Defects in this protein cause Friedreich ataxia. Recombinant Frataxin protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CyaY, FA, FARR, FRDA, X25, FXN, Friedreich ataxia protein. NCBI no.: NP_000135
    Molecular Weight
    21.1 kDa (190aa), confirmed by MALDI-TOF.
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Cell Size
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