Aspartate beta Hydroxylase Protein (AA 75-270) (His tag)
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- Target See all Aspartate beta Hydroxylase (ASPH) Proteins
- Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 75-270
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Aspartate beta Hydroxylase protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- ASPH, 75-270aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ASPH Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol
- Storage
- 4 °C
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- Target
- Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
- Alternative Name
- ASPH (ASPH Products)
- Synonyms
- AAH Protein, BAH Protein, CASQ2BP1 Protein, HAAH Protein, JCTN Protein, junctin Protein, 2310005F16Rik Protein, 3110001L23Rik Protein, AI848629 Protein, AW261690 Protein, AW561901 Protein, C79816 Protein, cI-37 Protein, aah Protein, bah Protein, jctn Protein, MGC107896 Protein, cb971 Protein, fb69e10 Protein, fc06d04 Protein, fc95a08 Protein, wu:fb69e10 Protein, wu:fc06d04 Protein, wu:fc95a08 Protein, aspartate beta-hydroxylase Protein, aspartate-beta-hydroxylase Protein, aspartate beta-hydroxylase L homeolog Protein, ASPH Protein, Asph Protein, asph Protein, asph.L Protein
- Background
- ASPH (Aspartate beta-hydroxylase) is a widely-expressed type II membrane protein involved in calcium homeostasis. Located in the endoplasmic reticulum, ASPH specifically hydroxylates an Asp or Asn residue in the epidermal growth factor-like (EGF) domains of several proteins, using iron as a cofactor. While all ASPH variants are expressed in skeletal muscle, only some are detected in heart, brain, pancreas, placenta, lung, liver, and kidney tissues. Recombinant human ASPH protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: AAH, BAH, CASQ2BP1, HAAH, JCTN, junctin, Aspartyl/asparaginyl beta-hydroxylase ASP beta hydroxylase, Aspartyl/asparaginyl beta hydroxylase, Peptide aspartate beta dioxygenase,. NCBI no.: NP_001158227
- Molecular Weight
- 24.5 kDa (217aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- Positive Regulation of Endopeptidase Activity
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