EIF2S1 Protein (AA 1-315) (His tag)

Catalog No. ABIN667786

Product Details

Target: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Protein Type: Recombinant

Protein Characteristics: AA 1-315

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This EIF2S1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: EIF2S1, 1-315aa, Human, His tag, E.coli

Purity: > 85 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl

Storage: 4 °C

Target Details

Target: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Alternative Name: EIF2S1 (EIF2S1 Products)

Synonyms: EIF-2 Protein, EIF-2A Protein, EIF-2alpha Protein, EIF2 Protein, EIF2A Protein, Eif2s1 Protein, eif2s1l Protein, fb36a08 Protein, wu:fb36a08 Protein, zgc:56510 Protein, 0910001O23Rik Protein, 2410026C18Rik Protein, 35kDa Protein, Eif2a Protein, eIF2alpha Protein, eif2a Protein, CG9946 Protein, Dmel\\CG9946 Protein, Eif2alpha Protein, IF2A_DROME Protein, M(1)14C Protein, M(1)19-153 Protein, M(1)8e3-10 Protein, deIF2alpha Protein, eIF-2 Protein, eIF-2 a Protein, eIF-2 alpha Protein, eIF2 alpha Protein, eIF2-alpha Protein, eIF2a Protein, eiF-2alpha Protein, elF2alpha Protein, l(1)14Cf Protein, l(1)19-153 Protein, eukaryotic translation initiation factor 2 subunit alpha Protein, eukaryotic translation initiation factor 2, subunit 1 alpha a Protein, eukaryotic translation initiation factor 2, subunit 1 alpha Protein, eukaryotic translation initiation factor 2 alpha subunit Protein, Eukaryotic translation initiation factor 2 subunit 1 Protein, eukaryotic translation initiation factor 2 subunit alpha L homeolog Protein, eukaryotic translation Initiation Factor 2alpha Protein, EIF2S1 Protein, eif2s1a Protein, Eif2s1 Protein, eif2s1 Protein, LOC693063 Protein, CNI00230 Protein, THAPSDRAFT_105 Protein, if2a Protein, eif2s1.L Protein, eIF-2alpha Protein

Background: EIF2S1, also known as eIF2 alpha, is the alpha subunit of the translation initiation factor eIF2 complex which catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. The phosphorylation state of eIF2S1 controls the rate of tRNA translation. When eIF2 alpha is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2S1 is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation. Recombinant human EIF2S1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A, Eukaryotic translation initiation factor 2 subunit 1 EIF 2 alpha, EIF 2, EIF 2A, EIF 2alpha, EIF2 alpha, Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa, Eukaryotic translation initiation factor 2 subunit 1 alpha, # Eukaryotic translation initiation factor 2 subunit alpha. NCBI no.: NP_004085

Molecular Weight: 38.2 kDa (335aa) confirmed by MALDI-TOF

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C