IMPDH1 Protein (AA 1-514) (His tag)
-
- Target See all IMPDH1 Proteins
- IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-514
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IMPDH1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- IMPDH1, 1-514aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product IMPDH1 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol
- Storage
- 4 °C
-
- Target
- IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))
- Alternative Name
- IMPDH1 (IMPDH1 Products)
- Synonyms
- IMPD Protein, IMPD1 Protein, LCA11 Protein, RP10 Protein, sWSS2608 Protein, B930086D20Rik Protein, IMPD 1 Protein, IMPDH 1 Protein, D3 Protein, IMPD 1b Protein, IMPDH 1b Protein, IMPDH1 Protein, id:ibd5035 Protein, si:dkey-31f5.7 Protein, wu:fa09h11 Protein, wu:fa99c03 Protein, zgc:113446 Protein, imp Protein, imp1 Protein, imp2 Protein, IMPD 1a Protein, IMPDH 1a Protein, zgc:91911 Protein, inosine monophosphate dehydrogenase 1 Protein, inosine-5'-monophosphate dehydrogenase 1 Protein, IMP (inosine 5'-monophosphate) dehydrogenase 1b Protein, IMP (inosine 5'-monophosphate) dehydrogenase 1 Protein, IMP (inosine 5'-monophosphate) dehydrogenase 1a Protein, IMPDH1 Protein, Impdh1 Protein, LOC100442769 Protein, impdh1 Protein, impdh1b Protein, impdh1.L Protein, impdh1a Protein
- Background
- Inosine-5'-monophosphate dehydrogenase 1, also known as IMPDH1 catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). Also, IMPDH1 is a ubiquitously expressed enzyme, functioning as a homotetramer, which catalyzed the rate-limiting step in de novo synthesis of guanine nucleotides. As such, it plays an important role in cyclic nucleoside metabolism within photoreceptors. Defects in the IMPDH1 gene are a cause of retinitis pigmentosa type 10. Recombinant human IMPDH1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: IMPD, IMPD1, LCA11, RP10, Inosine-5'-monophosphate dehydrogenase 1 IMP dehydrogenase 1. NCBI no.: NP_001136045
- Molecular Weight
- 57.5 kDa (534aa), confirmed by MALDI-TOF
- Pathways
- Ribonucleoside Biosynthetic Process
-