NCF1 Protein (AA 1-390) (His tag)

Catalog No. ABIN7279100

Product Details

Target: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Protein Type: Recombinant

Protein Characteristics: AA 1-390

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NCF1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: NCF1, 1-390aa, Human, His tag, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl

Storage: 4 °C

Target Details

Target: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Alternative Name: NCF1 (NCF1 Products)

Synonyms: NCF1A Protein, NOXO2 Protein, SH3PXD1A Protein, p47phox Protein, Ncf-1 Protein, p47 Protein, neutrophil cytosolic factor 1 Protein, NCF1 Protein, Ncf1 Protein

Background: Neutrophil cytosolic factor 1, also known as NCF1, is a cytosolic subunit of neutrophil NADPH oxidase. NCF1, along with NCF2 and a membrane bound cytochrome b558, is required for activation of the latent NADPH oxidase necessary for superoxide production. Defects in NCF1, often resulting from recombination between NCF1 and a nearby homologous pseudogene, cause chronic granulomatous disease. Recombinant human NCF1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: NCF1A, NOXO2, p47phox, SH3PXD1A, Neutrophil cytosolic factor 1. NCBI no.: AAH02816

Molecular Weight: 45.7 kDa (398aa) confirmed by MALDI-TOF

Pathways: PI3K-Akt Signaling