Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

UPP1 Protein (AA 1-310) (His tag)

UPP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667819
  • Target See all UPP1 Proteins
    UPP1 (Uridine Phosphorylase 1 (UPP1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-310
    Origin
    • 8
    • 1
    • 1
    • 1
    Human
    Source
    • 7
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This UPP1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    UPP1, 1-310aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product UPP1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 200mM NaCl
    Storage
    4 °C
  • Target
    UPP1 (Uridine Phosphorylase 1 (UPP1))
    Alternative Name
    UPP1 (UPP1 Products)
    Synonyms
    upp1 Protein, UDRPASE Protein, UP Protein, UPASE Protein, UPP Protein, im:6911242 Protein, zgc:110755 Protein, AI325217 Protein, UPase Protein, UdRPase Protein, Up Protein, Upp Protein, uridine phosphorylase 1 Protein, uridine phosphorylase Protein, upp1 Protein, NP_RS08675 Protein, Tsp_02326 Protein, UPP1 Protein, Upp1 Protein
    Background
    Uridine phosphorylase 1, also known as UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The reaction products are then utilized as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. The expression levels and the enzymatic activity of UPP1 are higher in human solid tumors than in adjacent normal tissues. In addition, UPP1 controls the homeostatic regulation of uridine concentration in plasma and tissues and plays a role in the intracellular activation of 5-fluorouracil. Recombinant human UPP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Uridine phosphorylase 1, UP, UPASE, UPP, UrdPase 1. NCBI no.: NP_853628
    Molecular Weight
    36 kDa (330aa), confirmed by MALDI-TOF
    Pathways
    Ribonucleoside Biosynthetic Process
You are here:
Support