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HSD17B11 Protein (AA 20-285) (His tag)

HSD17B11 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667857
  • Target See all HSD17B11 Proteins
    HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 20-285
    Origin
    • 6
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HSD17B11 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    HSD17B11, 20-285aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product HSD17B11 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol
    Storage
    4 °C
  • Target
    HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))
    Alternative Name
    HSD17B11 (HSD17B11 Products)
    Synonyms
    17BHSD11 Protein, DHRS8 Protein, PAN1B Protein, RETSDR2 Protein, SDR16C2 Protein, Dhrs8 Protein, HSD17B13 Protein, MGC84756 Protein, HSD17B11 Protein, Pan1b Protein, SDR2 Protein, retSDR2 Protein, 17-beta-HSD 11 Protein, 17-beta-HSD XI Protein, 17bHSD11 Protein, 17betaHSD11 Protein, 17betaHSDXI Protein, hydroxysteroid 17-beta dehydrogenase 11 Protein, hydroxysteroid (17-beta) dehydrogenase 11 Protein, hydroxysteroid (17-beta) dehydrogenase 11 L homeolog Protein, estradiol 17-beta-dehydrogenase 11 Protein, HSD17B11 Protein, Hsd17b11 Protein, hsd17b11.L Protein, hsd17b11 Protein, LOC100348005 Protein, LOC100520923 Protein
    Background
    HSD17B11, also known as DHRS8 (dehydrogenase/reductase SDR family member 8), belongs to the HSD17B family of proteins, which regulate the availability of steroids within various tissues throughout the body. It is widely expressed with highest levels found in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary and heart as well as in steroidogenic cells. This protein converts androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone, suggesting it may participate in androgen metabolism during steroidogenesis. Recombinant human HSD17B11 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Hydroxysteroid (17-beta) dehydrogenase 11, 17BHSD11, DHRS8, PAN1B, RETSDR2, SDR16C2. NCBI no.: NP_057329
    Molecular Weight
    31.4 kDa (287aa), confirmed by MALDI-TOF
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