WHSC2 Protein (AA 1-539) (His tag)
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- Target See all WHSC2 Proteins
- WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-539
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This WHSC2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- WHSC2, 1-539aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product WHSC2 Protein
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Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2) (AA 429-527) protein (GST tag)
WHSC2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2) (AA 1-539) protein (His tag)WHSC2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2) (AA 1-528) protein (GST tag)WHSC2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2) (AA 1-528) protein (His tag)Crystallography grade WHSC2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2) (AA 1-530) protein (His tag)Crystallography grade WHSC2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2) protein (Myc-DYKDDDDK Tag)WHSC2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 20% glycerol
- Storage
- 4 °C
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- Target
- WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
- Alternative Name
- WHSC2 (WHSC2 Products)
- Synonyms
- BcDNA:SD07139 Protein, CG5874 Protein, Dmel\\CG5874 Protein, NELF Protein, NELF-A Protein, Whsc2 Protein, fi75f03 Protein, whsc2 Protein, wu:fi75f03 Protein, MGC85474 Protein, WHSC2 Protein, nelfa Protein, nelf-a Protein, p/okcl.15 Protein, Whsc2h Protein, Negative elongation factor A Protein, negative elongation factor complex member A Protein, negative elongation factor complex member A L homeolog Protein, negative elongation factor complex member A, Whsc2 Protein, Nelf-A Protein, Nelfa Protein, nelfa Protein, nelfa.L Protein, NELFA Protein
- Background
- WHSC2, also known as NELF-A, is a protein factor required for DRB-sensitive transcription. This protein is one of the five components of the multisubunit NELF complex that cooperates with DSIF to repress RNA polymerase II elongation. Wolf-Hirschhorn syndrome is a multiple malformation syndrome characterized by mental and developmental defects resulting from a hemizygous deletion of the distal short arm of chromosome 4 (4p16.3). Recombinant human WHSC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Wolf-Hirschhorn syndrome candidate 2, NELF-A, NELFA, P/OKcl.15, Negative elongation factor A. NCBI no.: NP_005654
- Molecular Weight
- 60.6 kDa (559aa)
- Pathways
- Chromatin Binding
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