Grancalcin Protein (AA 1-217) (His tag)
-
- Target See all Grancalcin (GCA) Proteins
- Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-217
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Grancalcin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- GCA, 1-217aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product GCA Protein
-
Grancalcin, EF-Hand Calcium Binding Protein (GCA) (AA 1-217) protein (His tag)
GCA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Grancalcin, EF-Hand Calcium Binding Protein (GCA) (AA 1-217) protein (GST tag)GCA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Grancalcin, EF-Hand Calcium Binding Protein (GCA) (AA 1-220) protein (Strep Tag)Crystallography grade GCA Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Grancalcin, EF-Hand Calcium Binding Protein (GCA) protein (Myc-DYKDDDDK Tag)GCA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by BCA assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl
- Storage
- 4 °C
-
- Target
- Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
- Alternative Name
- GCA (GCA Products)
- Synonyms
- Grancalcin Protein, 5133401E04Rik Protein, AI573844 Protein, GCL Protein, zgc:92027 Protein, grancalcin Protein, Grancalcin Protein, zgc:92027 Protein, GCA Protein, gran Protein, LOC100280890 Protein, Gca Protein
- Background
- GCA, also known as Grancalcin, is calcium-binding protein that is especially abundant in human neutrophils. It belongs to the penta EF-hand (PEF) subfamily of EF-hand proteins, which also comprises calpain, sorcin, peflin, and ALG-2. This protein undergoes important conformational changes upon binding of calcium, which subsequently exposes hydrophobic amino acid residues, which direct the protein to hydrophobic surfaces. It interacts with L-plastin, a protein known to have actin bundling activity, which suggests that GCA may play a role in the regulation of neutrophils adhesion. Recombinant human GCA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Grancalcin, GCL. NCBI no.: NP_036330
- Molecular Weight
- 26.1 kDa (237aa), confirmed by MALDI-TOF
-
