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Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) (AA 1-228) protein (His tag)

CMPK1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667894
  • Target See all Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) Proteins
    Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-228
    Origin
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 88
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    His tag
    Application
    SDS-PAGE (SDS)
    Characteristics
    CMPK1, 1-228aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product CMPK1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT, 100mM NaCl
    Storage
    4 °C
  • Target
    Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    Alternative Name
    CMPK1 (CMPK1 Products)
    Synonyms
    CK Protein, CMK Protein, CMPK Protein, UMK Protein, UMP-CMPK Protein, UMPK Protein, UMP/CMPK Protein, PSPTO1749 Protein, cmpk1 Protein, fb52d08 Protein, fk47a07 Protein, ump Protein, wu:fb52d08 Protein, wu:fk47a07 Protein, zgc:56452 Protein, Cmpk Protein, RGD1310116 Protein, cmpk Protein, 0610011D08Rik Protein, UMP-CMPk Protein, UCK Protein, cytidine/uridine monophosphate kinase 1 Protein, cytidylate kinase Protein, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic Protein, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic S homeolog Protein, cytidylate kinase Cmk Protein, cytidine monophosphate (UMP-CMP) kinase 1 Protein, CMPK1 Protein, cmk Protein, cmpk1 Protein, cmpk Protein, Cmpk1 Protein, cmpk1.S Protein, Mrub_0478 Protein, MMAH_RS06670 Protein, TAGG_RS04320 Protein, Trad_0784 Protein, Deba_2713 Protein, Toce_1154 Protein, VDIS_RS03585 Protein, Fbal_1939 Protein, Ilyop_1379 Protein, Lbys_3481 Protein, Calni_0093 Protein, Ftrac_1556 Protein, Ocepr_1777 Protein
    Background
    CMPK1, also known as UMP-CMP kinase and deoxycytidylate kinase, is an enzyme that catalyzes the phosphoryl transfer from ATP to UMP, CMP and dCMP. This enzymatic reaction leads to the formation of ADP and the corresponding nucleoside diphosphate, which are required for cellular nucleic acid synthesis. It also plays an important role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. Recombinant human CMPK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: UMP-CMP kinase, CMK, CMPK, RP11-511I2.1, UMK, UMP-CMPK, UMPK. NCBI no.: NP_057392
    Molecular Weight
    28.0 kDa (248aa), confirmed by MALDI-TOF
    Pathways
    Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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