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QDPR Protein (AA 1-244) (His tag)

QDPR Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667949
  • Target See all QDPR Proteins
    QDPR (Quinoid Dihydropteridine Reductase (QDPR))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-244
    Origin
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 3
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This QDPR protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    QDPR, 1-244aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product QDPR Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT.
    Storage
    4 °C
  • Target
    QDPR (Quinoid Dihydropteridine Reductase (QDPR))
    Alternative Name
    QDPR (QDPR Products)
    Synonyms
    DHPR Protein, PKU2 Protein, SDR33C1 Protein, 2610008L04Rik Protein, D5Ertd371e Protein, Dhpr Protein, QDPR Protein, qdpr Protein, MGC131372 Protein, DDBDRAFT_0168923 Protein, DDBDRAFT_0237752 Protein, DDB_0168923 Protein, DDB_0237752 Protein, CG4665 Protein, Dmel\\CG4665 Protein, si:ch211-89f22.2 Protein, quinoid dihydropteridine reductase Protein, quinoid dihydropteridine reductase S homeolog Protein, dihydropteridine reductase Protein, Dihydropteridine reductase Protein, bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB Protein, quinoid dihydropteridine reductase a Protein, QDPR Protein, Qdpr Protein, qdpr Protein, qdpr.S Protein, Dhpr Protein, nfnB Protein, LOC5568428 Protein, dhpr Protein, qdpra Protein
    Background
    QDPR is a member of the short-chain dehydrogenases/reductase(SDR) family of enzymes. Functioning as a homodimer, QDPR plays an important role in the recycling of tetrahydrobiopterin (BH4), an essential cofactor for the hydroxylation of the aromatic amino acids (tryptophan, tyrosine and phenylalanine). More specifically, QDPR catalyzes the regeneration of BH4 from quinonoid dihydrobiopterin (qBH2), the product generated from the hydroxylation reactions. Mutations in the gene encoding QDPR can lead to phenylketonuria II. Recombinant human QDPR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Quinoid dihydropteridine reductase., DHPR, FLJ42391, PKU2, SDR33C1. NCBI no.: NP_000311
    Molecular Weight
    28.2 kDa (267aa), confirmed by MALDI-TOF
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