IMPDH2 Protein (AA 1-514) (His tag)
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- Target See all IMPDH2 Proteins
- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-514
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IMPDH2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- IMPDH2, 1-514aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product IMPDH2 Protein
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IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 1-514) protein (GST tag)
IMPDH2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 1-514) protein (His tag)IMPDH2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 2-514) protein (His tag)Crystallography grade IMPDH2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 2-514) protein (His tag)Crystallography grade IMPDH2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) (AA 5-514), (partial) protein (GST tag)IMPDH2 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95 % SDS, WB, ELISA
IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) protein (Myc-DYKDDDDK Tag)IMPDH2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 150mM NaCl
- Storage
- 4 °C
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- Target
- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
- Alternative Name
- IMPDH2 (IMPDH2 Products)
- Synonyms
- imp2 Protein, impd2 Protein, impdh-ii Protein, impdh2 Protein, IMPD2 Protein, IMPDH-II Protein, IMPD 2 Protein, IMPDH 2 Protein, cb635 Protein, wu:fb64g02 Protein, wu:fc43f09 Protein, IMPD Protein, inosine monophosphate dehydrogenase 2 Protein, IMP (inosine 5'-monophosphate) dehydrogenase 2 Protein, inosine 5'-phosphate dehydrogenase 2 Protein, IMPDH2 Protein, impdh2.S Protein, impdh2 Protein, Impdh2 Protein
- Background
- IMPDH2 belongs to the IMPDH/GMPR family. It catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. Also IMPDH1 and IMPDH2 are targets for the important immunosuppressive drug, mycophenolic acid (MPA). Recombinant human IMPDH2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Inosine-5'-monophosphate dehydrogenase 2, IMPD2, IMPDH-II. NCBI no.: NP_000875
- Molecular Weight
- 58.0kDa (534aa)
- Pathways
- Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome
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