MAPK14 Protein (AA 1-360) (His tag)

Catalog No. ABIN667983

Product Details

Target: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Protein Type: Recombinant

Protein Characteristics: AA 1-360

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This MAPK14 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: MAPK14, 1-360aa, Human, His tag, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 100mM NaCl

Storage: 4 °C

Target Details

Target: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Alternative Name: MAPK14 (MAPK14 Products)

Synonyms: CSBP Protein, CSBP1 Protein, CSBP2 Protein, CSPB1 Protein, EXIP Protein, Mxi2 Protein, PRKM14 Protein, PRKM15 Protein, RK Protein, SAPK2A Protein, p38 Protein, p38ALPHA Protein, CRK1 Protein, Csbp1 Protein, Csbp2 Protein, Exip Protein, Hog Protein, Prkm14 Protein, Prkm15 Protein, Sapk2A Protein, p38Hog Protein, p38alpha Protein, p38b Protein, zp38b Protein, MAPK14 Protein, 186F5S Protein, BG:DS00797.3 Protein, CG7393 Protein, D-p38 Protein, D-p38 MAPK Protein, D-p38b Protein, Dm p38b Protein, Dmel\\CG7393 Protein, Dmp38b Protein, Dp38 Protein, Dp38b Protein, ESTS:186F5S Protein, Mpk34C Protein, anon-sts23 Protein, dp38b Protein, p38 MAPK Protein, p38 beta Protein, p38B Protein, p38Kb Protein, p38beta Protein, Crk1 Protein, p38-alpha Protein, p38MAPK Protein, p38a Protein, csbp Protein, mapk14a Protein, mxi2 Protein, sapk2 Protein, sapk2a Protein, AP22.98 Protein, AP22_98 Protein, ATMPK14 Protein, mitogen-activated protein kinase 14 Protein, SAPK2a Protein, MAP kinase 14A Protein, MAP kinase p38a Protein, MAPK 14A Protein, fk28c03 Protein, hm:zeh1243 Protein, wu:fk28c03 Protein, zp38a Protein, P38C-CRK Protein, mitogen-activated protein kinase 14 Protein, mitogen activated protein kinase 14 Protein, mitogen-activated protein kinase 14b Protein, p38b MAP kinase Protein, mitogen-activated protein kinase 14 S homeolog Protein, mitogen-activated protein kinase 14a Protein, CRK proto-oncogene, adaptor protein Protein, MAPK14 Protein, Mapk14 Protein, mapk14b Protein, p38b Protein, mapk14.S Protein, MPK14 Protein, mapk14a Protein, CRK Protein

Background: MAPK14 (Mitogen-activated protein kinase 14) is a member of the MAP kinase family. MAPK14 is most closely related to p38 MAP kinases(MAPKs). MAPKs are activated primarily in response to inflammatory cytokines and cellular stress, and inhibitors which target the MAPK14 and MAPK11 have shown potential for the treatment of inflammatory disease. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress-related transcription and cell cycle regulation, as well as in genotoxic stress response. Recombinant human MAPK14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Mitogen-activated protein kinase 14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, p38, p38ALPHA, PRKM14, PRKM15, RK, SAPK2A. NCBI no.: NP_620581

Molecular Weight: 43.7kDa (383aa), confirmed by MALDI-TOF

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins