NAE1 Protein (AA 1-534) (His tag)
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- Target See all NAE1 Proteins
- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-534
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NAE1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- NAE1, 1-534aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NAE1 Protein
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NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-534) protein (GST tag)
NAE1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-534) protein (His tag)NAE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 2-534) protein (His tag)Crystallography grade NAE1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)NAE1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl
- Storage
- 4 °C
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- Target
- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
- Alternative Name
- NAE1 (NAE1 Products)
- Background
- NAE1 (NEDD8-activating enzyme E1 regulatory subunit) belongs to the ubiquitin-activating E1 family. This protein binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. NAE1 participates in a novel ubiquitinylation-related pathway involving the ubiquitin-like molecule NEDD8. Also, this protein is required for cell cycle progression through the S/M checkpoint. Recombinant human NAE1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: NEDD8 activating enzyme E1 subunit 1, A-116A10.1, APPBP1, HPP1, ula-1. NCBI no.: NP_003896
- Molecular Weight
- 62.7kDa (557aa)
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