DUSP10 Protein (AA 149-482) (His tag)
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- Target See all DUSP10 Proteins
- DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 149-482
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DUSP10 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- DUSP10, 149-482aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product DUSP10 Protein
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Dual Specificity Phosphatase 10 (DUSP10) (AA 1-140) protein (GST tag)
DUSP10 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Dual Specificity Phosphatase 10 (DUSP10) (AA 1-482) protein (Strep Tag)Crystallography grade DUSP10 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Dual Specificity Phosphatase 10 (DUSP10) (AA 1-483) protein (Strep Tag)Crystallography grade DUSP10 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Dual Specificity Phosphatase 10 (DUSP10) protein (His tag)DUSP10 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 50% glycerol, 200mM NaCl
- Storage
- 4 °C
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- Target
- DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
- Alternative Name
- DUSP10 (DUSP10 Products)
- Synonyms
- DUSP10 Protein, MKP-5 Protein, MKP5 Protein, 2610306G15Rik Protein, AI158871 Protein, Mkp-5 Protein, Mkp5 Protein, dual specificity phosphatase 10 Protein, DUSP10 Protein, Dusp10 Protein
- Background
- DUSP10 (Dual specificity protein phosphatase 10) belongs to the protein-tyrosine phosphatase family. Dual specificity protein phosphatases(DUSPs) inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. DUSP10 has been shown to interact with MAPK14 and MAPK8. When expressed in mammalian cells, DUSP10 blocks the enzymatic activation of MAP kinases with the selectivity p38 approximately JNK/SAPK >> ERK. Recombinant human DUSP10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Dual specificity protein phosphatase 10, MKP-5, MKP5. NCBI no.: NP_009138
- Molecular Weight
- 40.4kDa (359aa), confirmed by MALDI-TOF
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