LDLRAP1 Protein (AA 1-308) (His tag)
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- Target See all LDLRAP1 Proteins
- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-308
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LDLRAP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- LDLRAP1, 1-308aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product LDLRAP1 Protein
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Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) (AA 1-308) protein (His tag)
LDLRAP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) (AA 1-263) protein (GST tag)LDLRAP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) (AA 1-308) protein (Strep Tag)Crystallography grade LDLRAP1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) protein (Myc-DYKDDDDK Tag)LDLRAP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl
- Storage
- 4 °C
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- Target
- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
- Alternative Name
- LDLRAP1 (LDLRAP1 Products)
- Synonyms
- ARH Protein, ARH1 Protein, ARH2 Protein, FHCB1 Protein, FHCB2 Protein, AA691260 Protein, Arh Protein, Arh1 Protein, RGD1563417 Protein, arh Protein, arh1 Protein, arh2 Protein, fhcb1 Protein, fhcb2 Protein, xptb Protein, LDLRAP1 Protein, ldlrap1 Protein, sb:cb50 Protein, zgc:56121 Protein, zgc:158745 Protein, low density lipoprotein receptor adaptor protein 1 Protein, low density lipoprotein receptor adaptor protein 1 L homeolog Protein, low density lipoprotein receptor adaptor protein 1 S homeolog Protein, low density lipoprotein receptor adaptor protein 1a Protein, low density lipoprotein receptor adaptor protein 1b Protein, LDLRAP1 Protein, Ldlrap1 Protein, ldlrap1 Protein, ldlrap1.L Protein, ldlrap1.S Protein, ldlrap1a Protein, ldlrap1b Protein
- Background
- LDLRAP1 (Low density lipoprotein receptor adapter protein 1) is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. LDLRAP1 is a cytosolic adaptor that couples LDLR to endocytic machinery. Defects in LDLRAP1 are the cause of autosomal recessive hypercholesterolemia (ARH). ARH is a disorder caused by defective internalization of LDL receptors (LDLR) in the liver. Recombinant human LDLRAP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Low density lipoprotein receptor adaptor protein 1, ARH, ARH1, ARH2, FHCB1, FHCB2. NCBI no.: AAH29770
- Molecular Weight
- 36.1kDa (328aa), confirmed by MALDI-TOF
- Pathways
- Lipid Metabolism
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