GMP Synthase Protein (AA 1-693) (His tag)
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- Target See all GMP Synthase (GMPS) Proteins
- GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-693
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GMP Synthase protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- GMPS, 1-693aa , Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product GMPS Protein
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Guanine Monophosphate Synthetase (GMPS) (AA 108-215) protein (GST tag)
GMPS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Guanine Monophosphate Synthetase (GMPS) (AA 1-693) protein (GST tag)GMPS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Guanine Monophosphate Synthetase (GMPS) (AA 2-693) protein (His tag)Crystallography grade GMPS Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Guanine Monophosphate Synthetase (GMPS) (AA 2-693) protein (His tag)Crystallography grade GMPS Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Guanine Monophosphate Synthetase (GMPS) protein (Myc-DYKDDDDK Tag)GMPS Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
- Storage
- 4 °C
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- Target
- GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))
- Alternative Name
- GMPS (GMPS Products)
- Synonyms
- GMPS Protein, AA591640 Protein, AI047208 Protein, sb:cb632 Protein, wu:fb76b01 Protein, wu:fi05a09 Protein, zgc:66002 Protein, guanine monophosphate synthase Protein, guanine monophosphate synthase L homeolog Protein, guanine monophosphate synthetase Protein, GMPS Protein, gmps.L Protein, gmps Protein, Gmps Protein
- Background
- GMP synthase, also known as GMPS, is involved in purine biosynthesis. Existing as a homodimer, GMPS catalyzes the last step in the GMP synthesis pathway, namely the ATP-dependent amination of XMP to GMP. GMPS contains one GMP-binding domain and one glutamine amidotransferase type-1 domain through which it conveys its catalytic activity. Chromosomal translocations involving the gene encoding GMPS are associated with acute myeloid leukemias, suggesting a possible role for GMPS in carcinogenesis. Recombinant human GMPS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GMP synthase [glutamine-hydrolyzing], Glutamine amidotransferase, guanine monophosphate synthetase. NCBI no.: NP_003866
- Molecular Weight
- 79.2 kDa (717aa)
- Pathways
- Ribonucleoside Biosynthetic Process
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