HEXIM1 Protein (AA 1-359) (His tag)
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- Target See all HEXIM1 Proteins
- HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-359
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HEXIM1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- HEXIM1, 1-359aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product HEXIM1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
- Storage
- 4 °C
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- Target
- HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))
- Alternative Name
- HEXIM1 (HEXIM1 Products)
- Synonyms
- HEXIM1 Protein, fd44h02 Protein, hexim Protein, wu:fd44h02 Protein, zgc:162976 Protein, CLP1 Protein, EDG1 Protein, HIS1 Protein, MAQ1 Protein, 7330426E13Rik Protein, CLP-1 Protein, Clp1 Protein, Clp-1 Protein, hexamethylene bisacetamide inducible 1 Protein, hexamethylene bis-acetamide inducible 1 Protein, hexamethylene bis-acetamide inducible 1 L homeolog Protein, HEXIM1 Protein, hexim1 Protein, Hexim1 Protein, hexim1.L Protein
- Background
- HEXIM1 is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This protein has been shown to form a protein-RNA complex composed of 7SK small nuclear RNA and positive transcription elongation factor b (P-TEFb), which is composed of cyclin-dependent kinase 9 (CDK9) and cyclin T1, and to inhibit the kinase activity of CDK9, thereby suppressing RNA polymerase II-dependent transcriptional elongation. Recombinant HEXIM1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CLP1, EDG1, HIS1, MAQ1, Hexamethylene bis-acetamide inducible 1 Cardiac lineage protein 1, CLP 1, EDG 1, FLJ13562, Hexamethylene bis acetamide inducible 1, Hexamethylene bis acetamide inducible protein, Hexamethylene bis acetamide inducible transcript 1, HEXIM 1, HEXIM1 protein, HIS 1, HMBA inducible, MAQ 1, Menage a quatre 1. NCBI no.: NP_006451
- Molecular Weight
- 44.8 kDa (396aa), confirmed by MALDI-TOF.
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