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HEXIM1 Protein (AA 1-359) (His tag)

HEXIM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN668055
  • Target See all HEXIM1 Proteins
    HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-359
    Origin
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HEXIM1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    HEXIM1, 1-359aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product HEXIM1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
    Storage
    4 °C
  • Target
    HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))
    Alternative Name
    HEXIM1 (HEXIM1 Products)
    Synonyms
    HEXIM1 Protein, fd44h02 Protein, hexim Protein, wu:fd44h02 Protein, zgc:162976 Protein, CLP1 Protein, EDG1 Protein, HIS1 Protein, MAQ1 Protein, 7330426E13Rik Protein, CLP-1 Protein, Clp1 Protein, Clp-1 Protein, hexamethylene bisacetamide inducible 1 Protein, hexamethylene bis-acetamide inducible 1 Protein, hexamethylene bis-acetamide inducible 1 L homeolog Protein, HEXIM1 Protein, hexim1 Protein, Hexim1 Protein, hexim1.L Protein
    Background
    HEXIM1 is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This protein has been shown to form a protein-RNA complex composed of 7SK small nuclear RNA and positive transcription elongation factor b (P-TEFb), which is composed of cyclin-dependent kinase 9 (CDK9) and cyclin T1, and to inhibit the kinase activity of CDK9, thereby suppressing RNA polymerase II-dependent transcriptional elongation. Recombinant HEXIM1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CLP1, EDG1, HIS1, MAQ1, Hexamethylene bis-acetamide inducible 1 Cardiac lineage protein 1, CLP 1, EDG 1, FLJ13562, Hexamethylene bis acetamide inducible 1, Hexamethylene bis acetamide inducible protein, Hexamethylene bis acetamide inducible transcript 1, HEXIM 1, HEXIM1 protein, HIS 1, HMBA inducible, MAQ 1, Menage a quatre 1. NCBI no.: NP_006451
    Molecular Weight
    44.8 kDa (396aa), confirmed by MALDI-TOF.
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