Colony Stimulating Factor 1 (Macrophage) (CSF1) (Active) Protein

Details for Product No. ABIN780957, Supplier: Log in to see
Protein Name
  • CSF1
  • csf1-1
  • zgc:172186
  • CSF-1
  • MCSF
  • C87615
  • Csfm
  • op
  • colony stimulating factor 1
  • colony stimulating factor 1a (macrophage)
  • colony stimulating factor 1 (macrophage)
  • macrophage colony-stimulating factor 1
  • CSF1
  • csf1a
  • Csf1
  • LOC396599
Origin
Mouse (Murine)
52
24
12
2
Source
Escherichia coli (E. coli)
39
18
9
6
5
4
4
3
2
Protein Type
Recombinant
Biological Activity
Active
Application
In vitro Assay (in vitro), In vivo Studies (in vivo), ELISA, Western Blotting (WB)
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Sequence MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP
Specificity Recombinant mouse MIP-1alpha is a non-glycosylated protein, containing 69 amino acids, with a molecular weight of 7.8 kDa.
Cross-Reactivity Human
Purity ≥ 95%
Sterility Sterile filtered
Endotoxin Level ≤ 1.00 LAL (EUs/ug)
ProductDetails: Biological Activity Comment
  • Bioactivity Assay: NFS-60 cell proliferation
  • Bioactivity Acceptance Criteria ED50 (ng/ml): 10 ng/mL
  • Bioactivity Acceptance Criteria (Units/mg): 1 x 10^5 units/mg
Background Macrophage colony stimulating factor (M-CSF) is a hematopoietic growth factor that is widely produced by a variety of cells. M-CSF stimulates the proliferation and differentiation of hematopoietic stem cells into monocyte and macrophage cell types. M-CSF also acts through the colony stimulating factor 1 receptor (CSF1R) to modulate processes involved in immunology, bone metabolism, fertility, and pregnancy. Human M-CSF shows activity on mouse cells, however, mouse CSF shows no activity on human cells.

Alternate Names: MGI-IM, CSF-1
Molecular Weight Dimer: 18.2/36.4 MW Monomer/Total (kDa)
UniProt P07141
Pathways RTK Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Media Components: Luria Broth

Restrictions For Research Use only
Format Lyophilized
Reconstitution Sterile water at 0.1 mg/mL
Buffer Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing : 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Preservative Without preservative
Storage 4 °C/-20 °C/-80 °C
Storage Comment 12 months from date of receipt when stored at -20°C to-80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.
Expiry Date 12 months
Supplier Images
 image for Colony Stimulating Factor 1 (Macrophage) (CSF1) (Active) protein (ABIN780957) Colony Stimulating Factor 1 (Macrophage) (CSF1) (Active) protein
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