TNFRSF10B Protein (AA 52-212) (Fc Tag)
-
- Target See all TNFRSF10B Proteins
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 52-212
-
Origin
- Human
-
Source
- HEK-293T Cells
- Purification tag / Conjugate
- This TNFRSF10B protein is labelled with Fc Tag.
- Application
- ELISA
- Specificity
- Binds human and mouse TRAIL. Other species not tested.
- Characteristics
- Inhibits soluble TRAIL-induced apoptosis in a concentration range of 0.5-10 µg/mL. Concentrations of rhTRAIL-R2:Fc required to inhibit may vary depending on the cell type studied and on the concentration of sTRAIL used to kill cells. The extracellular domain (AA 52-212) of human TRAIL-R2 fused to the Fc portion of human IgG1.
- Purification
- Purified protein (LAL).
- Purity
- 95 % as determined by SDS-PAGE.
- Top Product
- Discover our top product TNFRSF10B Protein
-
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) protein (His-Avi Tag,Biotin)
TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 53-180) protein (His tag)TNFRSF10B Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) protein (His-Avi Tag)TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) protein (Fc Tag)TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) protein (mFc Tag)TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-180) protein (His-DYKDDDDK-Strep II Tag)TNFRSF10B Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-210) protein (His-DYKDDDDK-Strep II Tag)TNFRSF10B Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) (Active) protein (Fc Tag)TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (Active) proteinTNFRSF10B Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 52-183) protein (His tag)TNFRSF10B Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
-
- Application Notes
- ELISA: Use at 1 µg/mL. (capture)
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Storage
- -20 °C
-
- Target
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
- Alternative Name
- TRAIL-R2 (TNFRSF10B Products)
- Synonyms
- TNFRSF10B Protein, dr5 Protein, cd262 Protein, killer Protein, trick2 Protein, trickb Protein, xDR-M1 Protein, xDR-M2 Protein, ztnfr9 Protein, trailr2 Protein, trick2a Protein, trick2b Protein, CD262 Protein, DR5 Protein, KILLER Protein, KILLER/DR5 Protein, TRAIL-R2 Protein, TRAILR2 Protein, TRICK2 Protein, TRICK2A Protein, TRICK2B Protein, TRICKB Protein, ZTNFR9 Protein, Ly98 Protein, MK Protein, tumor necrosis factor receptor superfamily, member 10b Protein, tumor necrosis factor receptor superfamily member 10b S homeolog Protein, tumor necrosis factor receptor superfamily member 10b L homeolog Protein, tumor necrosis factor receptor superfamily member 10b Protein, TNF receptor superfamily member 10b Protein, Tnfrsf10b Protein, TNFRSF10B Protein, tnfrsf10b.S Protein, tnfrsf10b.L Protein, tnfrsf10b Protein
- Background
- TRAIL receptors are members of the TNF family of proteins. TRAIL-R2 (DR5) is a 50 kDa transmembrane protein containing 2 cysteine- rich repeats in the extracellular portion and a cytoplasmic motif called a `death domain' (DD). Binding of TRAIL (APO-2L) to TRAIL-R2 can induce apoptosis. Other identified TRAIL receptors include TRAIL-R1 (DR4), which like TRAIL-R2 promotes apoptosis, and three receptors (TRAIL-R3, TRAIL-R4, and Osteoprotegerin) that are inhibitory. Synonyms: DR5, KILLER, TNFRSF 10B, CD262
- Molecular Weight
- ~46 kDa (SDS-PAGE)
- Pathways
- p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity
-
