alpha-Fetoprotein (AFP) Protein

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Protein Name
  • FETA
  • HPAFP
  • alpha-fetoprotein
  • alpha fetoprotein
  • AFP
  • Afp
Origin
Human
42
13
6
3
3
2
1
Source
Human
26
21
8
2
2
2
2
1
1
Protein Type
Native
Application
ELISA
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Characteristics Purified native Human AFP protein
Protein Source: Human cord serum
Purity > 60 % pure
Background Alpha-fetoprotein is a protein that in humans is encoded by the AFP gene. This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin.
Description: Human cord serum.
Alternative Names: alpha-Fetoprotein protein, alpha-Fetoprotein antigen
Research Area Cancer
Pathways C21-Steroid Hormone Metabolic Process
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Buffer Lyophilized from PBS, pH 7.4, with 0.05 % NaN3.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid repeated freeze/thaw cycles.
Storage RT/-20 °C
Storage Comment Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Product cited in: Lee, Lee: "Regression of hepatocarcinoma cells using RNA aptamer specific to alpha-fetoprotein." in: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 521-7, 2012 (PubMed).