Tropomyosin Protein
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- Target See all Tropomyosin (TPM1) Proteins
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Protein Type
- Native
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Origin
- Human
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Source
- Human
- Characteristics
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Purified native Human Tropomyosin protein
Protein Source: Human cardiac tissue - Purity
- > 95 % pure
- Top Product
- Discover our top product TPM1 Protein
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Tropomyosin 1 (Alpha) (TPM1) (AA 1-245) protein (GST tag)
TPM1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Tropomyosin 1 (Alpha) (TPM1) (AA 91-188) protein (GST tag)TPM1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Tropomyosin 1 (Alpha) (TPM1) (AA 1-284) protein (Strep Tag)Crystallography grade TPM1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 7) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin 1 (Alpha) (TPM1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TPM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Buffer
- 10 mM TRIS-HCl, pH 7.4, with 50 mM NaCl, 5 mM beta-mercaptoethanol and 5 mM EDTA.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Target
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Alternative Name
- Tropomyosin (TPM1 Products)
- Synonyms
- alpha-fTM Protein, Tm7 Protein, tpm1 Protein, MGC84844 Protein, AA986836 Protein, AI854628 Protein, TM2 Protein, Tm3 Protein, Tmpa Protein, Tpm-1 Protein, alpha-TM Protein, Alpha-tm Protein, Tma2 Protein, Tmsa Protein, TPM1 Protein, fb37a09 Protein, tm Protein, wu:fb37a09 Protein, CH1 Protein, alpha-tm Protein, alpha-tropomyosin Protein, C15orf13 Protein, CMD1Y Protein, CMH3 Protein, HTM-alpha Protein, TMSA Protein, TPMA Protein, Tm1 Protein, zgc:171719 Protein, zgc:55951 Protein, zgc:77009 Protein, tropomyosin 1 (alpha) Protein, tropomyosin Protein, tropomyosin 1 Protein, tropomyosin 1, alpha Protein, alpha-tropomyosin Protein, tropomyosin 1 L homeolog Protein, TPM1 Protein, tm7 Protein, Tpm1 Protein, tpma Protein, tpm1.L Protein, Smp_044010.2 Protein, LOC732984 Protein, tpm1 Protein
- Background
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Tropomyosin is an actin-binding protein that regulates actin mechanics. It is important, among other things, for muscle contraction. Tropomyosin, along with the troponin complex, associate with actin in muscle fibers and regulate muscle contraction by regulating the binding of myosin. In resting muscle, tropomyosin overlays the myosin binding sites on actin, with a single tropomyosin molecule spanning 7 actin subunits, and is locked down in this position by troponin T (tropomyosin binding troponin) and troponin I (inhibitory troponin).
Description: Human cardiac tissue. - Pathways
- Regulation of Actin Filament Polymerization
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