ACVA Protein
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- Target See all ACVA Proteins
- ACVA (Activin A (ACVA))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Hi-5 Cells
- Sequence
- GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS
- Characteristics
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Purified recombinant Human Activin A protein
Expression System: Hi-5 cells
Bioactivity: The ED50 as determined by its ability to inhibit the proliferation of Mouse MPC-11 cells is ? 2 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg. - Purity
- > 95 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product ACVA Protein
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Activin A (ACVA) (AA 311-426) (Active) protein
ACVA Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Activin A (ACVA) (AA 311-426) proteinACVA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Activin A (ACVA) (AA 309-424) protein (His tag)ACVA Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Activin A (ACVA) (AA 309-424) protein (His tag)ACVA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Activin A (ACVA) (AA 21-426) (Active) protein (His tag)ACVA Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Comment
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Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.5 mg/mL. Do not vortex.
- Buffer
- Lyophilized from 10 mM Citric Acid pH 3.0.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- ACVA (Activin A (ACVA))
- Alternative Name
- Activin A (ACVA Products)
- Synonyms
- inhibin beta A subunit Protein, Inhba Protein
- Background
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Activin A is a TGF beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF beta antagonist, Follistatin.
Alternative Names: Activin beta-A protein, Inhibin beta-A protein - Molecular Weight
- 26 kDa
- Pathways
- Hormone Transport, Peptide Hormone Metabolism
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