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DEFB4A Protein

DEFB4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935228
  • Target See all DEFB4A (DEFB4) Proteins
    DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    Escherichia coli (E. coli)
    Sequence
    GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P
    Characteristics
    Purified recombinant Human BD2 protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to chemoattract immature human dendritic cells using a concentration of 10.0-100.0 ng/mL.
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product DEFB4 Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 10 mM Acetic Acid to a concentration of 0.1 - 1.0 mg/mL.
    Buffer
    Supplied lyophilized with no additives.
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))
    Alternative Name
    BD2 (DEFB4 Products)
    Synonyms
    BD-2 Protein, DEFB-2 Protein, DEFB102 Protein, DEFB2 Protein, DEFB4 Protein, HBD-2 Protein, SAP1 Protein, BD2 Protein, DEFB4P Protein, THP2 Protein, defensin beta 4A Protein, defensin beta 2 Protein, defensin beta 1 Protein, avian beta-defensin 4 Protein, defensin, beta 4A Protein, beta-defensin 2 Protein, defensin beta 4 Protein, beta defensin 2 Protein, DEFB4A Protein, Defb2 Protein, DEFB1 Protein, AvBD4 Protein, THP2 Protein, defb4 Protein, SBD2 Protein
    Background
    Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells.
    Alternative Names: BD-2, BD 2 protein, BD-2 protein, SAP1 protein, BD2, Skin-antimicrobial peptide 1 protein, BD 2 protein, BD 2, BD-2 protein
    Molecular Weight
    4.3 kDa
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