DEFB4A Protein
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- Target See all DEFB4A (DEFB4) Proteins
- DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P
- Characteristics
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Purified recombinant Human BD2 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract immature human dendritic cells using a concentration of 10.0-100.0 ng/mL. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product DEFB4 Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 10 mM Acetic Acid to a concentration of 0.1 - 1.0 mg/mL.
- Buffer
- Supplied lyophilized with no additives.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))
- Alternative Name
- BD2 (DEFB4 Products)
- Synonyms
- BD-2 Protein, DEFB-2 Protein, DEFB102 Protein, DEFB2 Protein, DEFB4 Protein, HBD-2 Protein, SAP1 Protein, BD2 Protein, DEFB4P Protein, THP2 Protein, defensin beta 4A Protein, defensin beta 2 Protein, defensin beta 1 Protein, avian beta-defensin 4 Protein, defensin, beta 4A Protein, beta-defensin 2 Protein, defensin beta 4 Protein, beta defensin 2 Protein, DEFB4A Protein, Defb2 Protein, DEFB1 Protein, AvBD4 Protein, THP2 Protein, defb4 Protein, SBD2 Protein
- Background
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Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells.
Alternative Names: BD-2, BD 2 protein, BD-2 protein, SAP1 protein, BD2, Skin-antimicrobial peptide 1 protein, BD 2 protein, BD 2, BD-2 protein - Molecular Weight
- 4.3 kDa
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