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C12orf57 Protein

C12orf57 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935298
  • Target See all C12orf57 Proteins
    C12orf57 (Chromosome 12 Open Reading Frame 57 (C12orf57))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 3
    • 3
    • 1
    • 1
    Mouse
    Source
    • 5
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA
    Characteristics
    Purified recombinant Mouse C10 protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to chemoattract Balb/c mouse spleen MNCs using a concentration range of 10.0-100.0 ng/mL.
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
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  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    C12orf57 (Chromosome 12 Open Reading Frame 57 (C12orf57))
    Alternative Name
    C10 (C12orf57 Products)
    Synonyms
    MRP-1 Protein, Scya6 Protein, c10 Protein, 2310033H05Rik Protein, C10 Protein, GRCC10 Protein, TEMTYS Protein, c12orf57 Protein, fc02g04 Protein, wu:fc02g04 Protein, zgc:86838 Protein, chemokine (C-C motif) ligand 6 Protein, gene rich cluster, C10 gene Protein, chromosome 12 open reading frame 57 Protein, chromosome 5 open reading frame, human C12orf57 Protein, chromosome 12 open reading frame 57 L homeolog Protein, Ccl6 Protein, Grcc10 Protein, C12orf57 Protein, C5H12orf57 Protein, c12orf57.L Protein, grcc10 Protein
    Background
    Mouse C10 belongs to the CC chemokine family and is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL3 or IL4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines. The mature protein contains 95 amino acid residues.
    Alternative Names: C-10, MRP-1 protein, C10, C-10 protein, C 10, CCL6 protein, C 10 protein, C-10 protein
    Molecular Weight
    10.7 kDa
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