GDF3 Protein
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- Target See all GDF3 Proteins
- GDF3 (Growth Differentiation Factor 3 (GDF3))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG
- Characteristics
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Purified recombinant Human GDF3 protein
Expression System: E.coli
Bioactivity: Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 100-150 ng/mL. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product GDF3 Protein
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Growth Differentiation Factor 3 (GDF3) (AA 251-364) protein (His-IF2DI Tag)
GDF3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Growth Differentiation Factor 3 (GDF3) (AA 265-364) protein (GST tag)GDF3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 3 (GDF3) (AA 1-364) protein (GST tag)GDF3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 3 (GDF3) (AA 251-364) protein (His tag)Crystallography grade GDF3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Growth Differentiation Factor 3 (GDF3) (AA 253-366) protein (His tag)Crystallography grade GDF3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.
- Buffer
- Supplied lyophilized with no additives.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- GDF3 (Growth Differentiation Factor 3 (GDF3))
- Alternative Name
- GDF3 (GDF3 Products)
- Synonyms
- KFS3 Protein, MCOP7 Protein, MCOPCB6 Protein, C78318 Protein, Gdf-3 Protein, Vgr-2 Protein, Vgr2 Protein, ecat9 Protein, RGD1564178 Protein, CVG1 Protein, der Protein, derriere Protein, gdf3-a Protein, vgr-2 Protein, vgr2 Protein, growth differentiation factor 3 Protein, growth differentiation factor 3 S homeolog Protein, GDF3 Protein, Gdf3 Protein, gdf3.S Protein
- Background
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GDF-3 is a member of the TGF beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes.
Alternative Names: GDF 3 protein, GDF-3 protein, GDF-3, GDF3, Growth/Differentiation Factor-3 protein, GDF-3 protein, GDF 3 - Molecular Weight
- 26 kDa
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