MSTN Protein
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- Target See all MSTN Proteins
- MSTN (Myostatin (MSTN))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- DFGLDCDEHS TESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGECEFV FLQKYPHTHL VHQANPRGSA GPCCTPTKMS PINMLYFNGK EQIIYGKIPA MVVDRCGCS
- Characteristics
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Purified recombinant Human Myostatin protein
Expression System: E.coli
Contaminants: Supplied lyophilized with no additives.
Bioactivity: Determined by its ability to inhibit the proliferation of MPC-11 cells. The expected ED50 for this effect is 17.0-25.0 ng/mL. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product MSTN Protein
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Myostatin (MSTN) (Active) protein
MSTN Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Myostatin (MSTN) (AA 267-375) protein (His-IF2DI Tag)MSTN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Myostatin (MSTN) (AA 1-375) protein (GST tag)MSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Myostatin (MSTN) (AA 121-202) protein (GST tag)MSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Myostatin (MSTN) (AA 241-310) protein (GST tag)MSTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Myostatin (MSTN) (AA 267-375) protein (His tag)Crystallography grade MSTN Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Myostatin (MSTN) (AA 268-376) protein (His tag)Crystallography grade MSTN Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with water to 0.1 - 1.0 mg/mL . Due to the solubility reasons the protein should be kept at low pH.
- Buffer
- Lyophilized with no additives.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- MSTN (Myostatin (MSTN))
- Alternative Name
- Myostatin (MSTN Products)
- Synonyms
- GDF-8 Protein, GDF8 Protein, gdf8 Protein, mstn Protein, zgc:109749 Protein, Gdf8 Protein, NV13143 Protein, MSLHP Protein, Cmpt Protein, myostatin Protein, myostatin b Protein, growth/differentiation factor 8 Protein, MSTN Protein, mstnb Protein, LOC5577632 Protein, BRAFLDRAFT_290840 Protein, Mstn Protein, mstn Protein
- Background
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Myostatin is a TGF beta family member that acts as an inhibitor of skeletal muscle growth. This muscle-specific cytokine interacts with Activin type I and type II receptors, and suppresses myoblast proliferation by arresting cell-cycle in the G1 phase. Suppression of myostatin activity facilitates muscle formation and may be useful in reducing and/or preventing adiposity and type-2 diabetes. Myostatin activity can be blocked by the Activin-binding protein Follistatin, and by the propeptide of Myostatin.
Alternative Names: GDF-8 protein - Molecular Weight
- 25 kDa
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