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CLCF1 Protein

CLCF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935688
  • Target See all CLCF1 Proteins
    CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 7
    • 4
    • 3
    Human
    Source
    • 10
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    MLNRTGDPGP GPSIQKTYDL TRYLEHQLRS LAGTYLNYLG PPFNEPDFNP PRLGAETLPR ATVDLEVWRS LNDKLRLTQN YEAYSHLLCY LRGLNRQAAT AELRRSLAHF CTSLQGLLGS IAGVMAALGY PLPQPLPGTE PTWTPGPAHS DFLQKMDDFW LLKELQTWLW RSAKDFNRLK KKMQPPAAAV TLHLGAHGF
    Characteristics
    Purified recombinant Human NNT1 protein
    Expression System: E.coli
    Bioactivity: NT-1/BCSF-3 weakly supports chick E8 DRG neurite outgrowth at a concentration of 1.0 ng/mL.
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product CLCF1 Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
    Alternative Name
    NNT1 (CLCF1 Products)
    Synonyms
    clc Protein, nr6 Protein, bsf3 Protein, nnt1 Protein, ciss2 Protein, CLCF1 Protein, BSF-3 Protein, BSF3 Protein, CISS2 Protein, CLC Protein, NNT-1 Protein, NNT1 Protein, NR6 Protein, Bsf3 Protein, Clc Protein, cardiotrophin like cytokine factor 1 Protein, cardiotrophin-like cytokine factor 1 Protein, clcf1 Protein, CLCF1 Protein, Clcf1 Protein
    Background
    NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-beta) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM.
    Alternative Names: NNT-1 protein, NNT-1 protein, Novel Neurtrophin-1/B-Cell Stimulating Factor-3 protein, Cardiotrophin-like cytokine protein, NNT 1, NNT 1 protein, NNT1, NNT-1
    Molecular Weight
    22.4 kDa
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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